Despitequalifyingforarmedforce,Karthik('Jayam'Ravi)preferstobeatrafficcopinOotyashebelievesthatsuchanoriskyjobwouldhelphimgetenoughtimetolookafterhiscutelittlesisterVidhya(BabyAnikha).KarthikalsohasashortlivedonesidelovestorywithRenu(LakshmiMenon),whoisadoctor.Whenahazardouschemicalinthenearbyindustrygetsleaked,adogconsumesitandturnsintoazombie.Asthedogbitesawatchman,hetoobecomesazombieandeventually,thevirusspreadsrapidlyacrossthetown.CanKarthiksavehissisterandthecity?
